Virtual Site as an aid to first-year learning

Courses run by the School of the Built Environment have a range of entry requirements that enable diverse students and those with lower academic qualifications to gain entry. This results in a particular challenge for the Documentation & Estimating module, which is a very practical, skillsand competence-based module. It is delivered to large tutorial cohorts of mixed courses, abilities, ages and experience. Many students need one-toone guidance to understand what, practically, they have to do. They are given the theory first in a lecture and then have practical tutorials to carry out assessed exercises with limited tutor contact time. The module includes some basic surveying techniques and a levelling exercise which involves the transfer of a level from an assumed benchmark to establish a temporary benchmark some distance away. Many students have problems with computation of results. In spite of a careful introduction and explanation of the use of the instruments and techniques, many students find it difficult to visualise what is happening

The Effect Of Product Involvement On Store Preference And Clothing Benefits Sought For African-American Female Students

Clothing is one of the most essential things that human bodies need for the multipurpose reasons. Such clothing has been recognized as the high involvement product for many years, resulting to one of the very interesting subjects in consumer research. The purpose of this study is to investigate the influences of clothing involvement on clothing store preference and clothing benefits sought for African-American female college students. This study demonstrates that African-American female college students are generally satisfied with the current ready-to-wear (RTW) clothing. To purchase such RTW clothing, internet store is revealed as one of very exciting shopping centers. Instead, catalog or mail ordering does not strongly attract to the African-American female college consumers. Compared to other involvement groups, high clothing involvement consumers are actively seeking for the fashion image, one of the factors in clothing benefits sought, as well as actively shopping at department store, specialty stores, outlet stores, and internet in Types of Stores. Interestingly, low involvement consumers are generally less interested in store preference or clothing benefits sought than other involvement groups except for the camouflage benefits

Testing for seasonal unit roots in heterogeneous panels

This paper uses the approach of Im, Pesaran and Shin (2003) to propose seasonal unit root tests for dynamic heterogeneous panels based on the means of the individuals HEGY test statistics. The standardised t-bar and F-bar statistics are simply averages of the HEGY tests across groups. These statistics converge to standard normal variates

Historical geography II: traces remain

The second report in this series turns to focus on the trace in relation to life-writing and biography in historical geography and beyond. Through attention to tracing journeys, located moments and listening to the presence of ghosts (Ogborn, 2005), this report seeks to highlight the range of different ways in which historical geographers have explored lives, deaths, and their transient traces through varied biographical terrains. Continuing to draw attention in historical geography to the darkest of histories, this piece will pivot on moments of discovering the dead to showcase the nuanced ways in which historical geography is opening doors into uncharted lives and unspoken histories

The estrogen-induced miR-19 downregulates secretory leucoprotease inhibitor expression in monocytes

Compared to females, males are more susceptible to acute viral and other respiratory tract infections that display greater severity and higher mortality. In contrast, females tend to fare worse with chronic inflammatory diseases. Circulating 17β-estradiol (E2) is a female-specific factor that may influence the progression of human lung diseases. Here we hypothesize that E2 modulates the inflammatory response of monocytes through microRNA (miRNA)-based modulation of secretory leucoprotease inhibitor (SLPI), an antiprotease with immunomodulatory effects. Monocytic cells were treated ± E2, and differentially expressed miRNAs were identified using PCR profiling. Cells were transfected with miRNA mimics or antimiRs and SLPI mRNA and protein levels were quantified. Luciferase activity assay using wildtype and ΔmiR-19a/b-SLPI3'UTR reporter constructs and chromatin immunoprecipitation on E2-treated monocytes were performed. E2 downregulated SLPI and upregulated miR-19 expression in monocytes. Transfection with premiR-19b reduced SLPI mRNA and protein levels and this effect was abrogated using antimiRs against miR-19b. miR-19b directly binds the SLPI 3'UTR. The mechanism responsible for E2-mediated upregulation of miR-19 occurs via increased MIR17HG promoter activity mediated by c-MYC. Overall E2 decreases SLPI expression in human monocytic cells, via changes in miRNA expression and highlights the potential for estrogen to modulate the innate immune system

Polarization fields in nitride nanostructures: ten points to think about

Macroscopic polarization, both of intrinsic and piezoelectric nature, is unusually strong in III-V nitrides, and the built in electric fields in the layers of nitride-based nanostructures, stemming from polarization changes at heterointerfaces, have a major impact on the properties of single and multiple quantum wells, high mobility transistors, and thin films. The concepts involved in the theory and applications of polarization in nitrides have encountered some resistance in the field. Here we discuss critically ten ``propositions'' aimed at clarifying the main controversial issues.Comment: RevTeX 5 pages, 2 embedded figure

Testing for seasonal unit roots in heterogeneous panels in the presence of cross section dependence

This paper presents two alternative methods for modifying the HEGY-IPS test in the presence of cross-sectional dependency. In general, the bootstrap method (BHEGY-IPS) has greater power than the method suggested by Pesaran (2007) (CHEGY-IPS), although for large T and high degree of cross-sectional dependency the CHEGY-IPS test dominates the BHEGY-IPS test

Radar for Monitoring Hurricanes from Geostationary Orbit

A document describes a scanning Doppler radar system to be placed in a geostationary orbit for monitoring the three-dimensional structures of hurricanes, cyclones, and severe storms in general. The system would operate at a frequency of 35 GHz. It would include a large deployable spherical antenna reflector, instead of conventional paraboloidal reflectors, that would allow the reflector to remain stationary while moving the antenna feed(s), and thus, create a set of scanning antenna beams without degradation of performance. The radar would have separate transmitting and receiving antenna feeds moving in spiral scans over an angular excursion of 4 from the boresight axis to providing one radar image per hour of a circular surface area of 5,300-km diameter. The system would utilize a real-time pulse-compression technique to obtain 300-m vertical resolution without sacrificing detection sensitivity and without need for a high-peakpower transmitter. An onboard data-processing subsystem would generate three-dimensional rainfall reflectivity and Doppler observations with 13-km horizontal resolution and line-of-sight Doppler velocity at a precision of 0.3 m/s

A missing dimension in measures of vaccination impacts

Immunological protection, acquired from either natural infection or vaccination, varies among hosts, reflecting underlying biological variation and affecting population-level protection. Owing to the nature of resistance mechanisms, distributions of susceptibility and protection entangle with pathogen dose in a way that can be decoupled by adequately representing the dose dimension. Any infectious processes must depend in some fashion on dose, and empirical evidence exists for an effect of exposure dose on the probability of transmission to mumps-vaccinated hosts [1], the case-fatality ratio of measles [2], and the probability of infection and, given infection, of symptoms in cholera [3]. Extreme distributions of vaccine protection have been termed leaky (partially protects all hosts) and all-or-nothing (totally protects a proportion of hosts) [4]. These distributions can be distinguished in vaccine field trials from the time dependence of infections [5]. Frailty mixing models have also been proposed to estimate the distribution of protection from time to event data [6], [7], although the results are not comparable across regions unless there is explicit control for baseline transmission [8]. Distributions of host susceptibility and acquired protection can be estimated from dose-response data generated under controlled experimental conditions [9]–[11] and natural settings [12], [13]. These distributions can guide research on mechanisms of protection, as well as enable model validity across the entire range of transmission intensities. We argue for a shift to a dose-dimension paradigm in infectious disease science and community health

Adsorption behavior of Eu(III) on partially Fe(III)- or Ti(IV)-coated silica

The adsorption behavior of Eu(III) onto silica surface, which was partially coated with Fe(III) or Ti(IV), was investigated to determine Fe(III) or Ti(IV) effects on the surface reaction of lanthanides on mineral surfaces in groundwater. Compared with a parallel uncoated silica, the Fe(III)-coated silica did not enhance the adsorption of Eu(III). However, enhanced adsorption of Eu(III) on the Ti(IV)-coated silica was observed by increasing the amount of Ti(IV) on the silica surface